Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

4、慧眼识香。邦德眼光敏锐,能辨认出孰敌孰友。这种品质常见于性开放者。007很容易识出对他有意的女人,有科学证明,帅哥往往擅长于此。
有趣的是,“真诚的问候”(unfeigned regards)又重回我们的视野——人们现在可以在印度服务中心的邮件上见到这一18世纪末的流行语。而更胜一筹的是这个签名,一个周五我收到了一则消息,末尾处写到:“周末好”(weekend well)。我差点将最佳名词使动用法奖也颁给它,不料最后一刻却杀出一匹黑马,一位顾问无意中说了句:“我们能把那件事冷毛巾一下吗?”(Can we cold towel that?)
如果你从平时身穿牛仔裤,t恤套装的搭配突然变成像面试时候穿的西装革履的的样子,这就更充分证实了你请了一天假去面试了。但如果你不这样做,而是穿的和平时在办公室穿的一样。你的老板都会注意到你的变化。然后,FOSS说,“走吧,别把这里当作了在麦当劳停车场面试。
在此背景下,白不仅仅是指肤色。你可以将其定义为“人种-民族多数”的成员,但这样有点拗口。它的真正含义是不会被定义为“他者”的特权。
Lufax is the largest, a subsidiary of China’s Ping An Insurance, which is Lufax’s largest shareholder.
雷文斯克罗夫特认为,如果他成为一名管理顾问,他的视野可能会相对狭窄。教学工作也有助于他变得愿意承担风险——这来之不易。“如果你曾站在30名会毫不犹豫地指出你的错误的青少年面前讲课,这种体验可能会让你变得愿意去尝试。”
Kate Winslet is another Brit who’s opted for the loo for her best actress Academy Award, which she was awarded for her complex role as a concentration camp guard in the 2008 adaptation of Bernhard Schlink’s novel, The Reader.
This list is composed of—The strongest, intelligent, desirable, popular, attractive, beautiful, successful women in 2015.
pollution
《丛林故事》将于2016年4月15日在全球上映。
比赛项目:
Rihanna, who came in at second place, earned her runner-up position "following another 12-month period in which she was absolutely bloody everywhere and yet we all entirely failed to get sick of her," per FHM.
Be Professional
这份排行榜基于对商学院及其2013届毕业生的调查。根据校友职业发展、学校创意生成以及学员和师资多样化对MBA课程进行评比。
The drama and the original game have a large fan base and enjoy great popularity in China, and even elsewhere in Asia.
竞争对手在网上的表现如何?谷歌的搜索广告关键词规划工具会帮助你解答这个问题。“搜索广告”这个词可能会令有些企业家望而却步,因为它似乎会要求你买广告位。但事实并非如此,只要有谷歌账号,任何人都能使用这个关键词规划工具(不过你首先必须点击Adwords的进入端口)。然后你可以使用关键词规划工具来看看在你从事的领域中,哪些关键词会吸引最多的搜索量,然后找出吸引流量的机会。
China in 2012: fixated on stability as the pressures mount without and within.
Hayley Williams remains a powerful up-front presence, a belter who can croon as convincingly as she can yelp. Her vocal bravado almost makes you forget that After Laughter is an up-close chronicle of her weariness with the world.
特斯拉是一款富人车。在均价85,000美元的水平线上,可以说买特斯拉的人没人会在意汽油钱。特斯拉在续航里程上的短板,也说明了它绝对不会是车主家里的唯一一辆车。如果这些人的新鲜劲儿过去了,特斯拉的订单储备就会缩水,也会像其它厂商一样需要为销量打拼。
达洛伊西奥说,我本来只是打算在苹果app store用一两英镑的价格出售这个软件,然后用赚来的钱给自己换台新电脑。我之前从没联系过任何投资商。而如今一个香港的亿万富翁竟然给我发电邮了,这太诡异了。第一封邮件我没有回覆,于是他们又给我发了第二封。2011年8月份,他的父母带着不可置信的心情陪他一同与维港投资的代表进行了会面。会谈结束后,达洛伊西奥获得了30万美元的种子投资。
目前,中国15座城市允许对某些国家的公民实行72小时免签证入境。上海、江苏和浙江则为来自某些国家的国际过境旅客提供144小时免签证停留。
And while you are at it, don't forget to celebrate the imperfections. While on a 10-day trek in the Himalayas, I learned that imperfections are beautiful too. The rough edges of the mountains, the heavy hail storms in the middle of the afternoon, were "inconvenient" but added to the beauty of the trek. I am acutely aware now that in my pursuit of perfection at work, I have often failed to recognize that imperfections are also a core part of our identity that needs to be preserved and not always changed.
5月7日-11日
Most common passwords of 2013:
6. The 2012 Ig Nobel Prize for Literature


《经济学人智库》发布了2016年世界生活成本报告,根据各种产品和服务的成本对各国进行了排名。
郭晶晶与霍启刚(香港近代富豪霍英东的孙子)的秘密恋情已经引起了全民的想象,人们似乎在关注运动员赛场表现之余,也愈加关心起他们的私人生活了。
[?'naunst]


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

的确,价格不是一切。但即使是看空者也同意:一切都有价格。
让我们看看2017年余下时间有哪些贸易动向:
Since its first release in 1995, many new versions and sequels have been created. However, fans say none could replace the breath-taking and tragic tale of the original.
The controlled test takes two-and-a-half hours and, according to theories, Nishi's score and subsequentIQ of 162 would be two points higher than famous physicist Einstein.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

In early November the government further tightened controls over outbound investment by requiring regulatory approval for some foreign acquisitions conducted through an offshore entity.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

该机构在2014年的一项调查显示,在完成两年教学的受访者当中,86%表示他们通过自己的工作为改变教育不平等采取了行动,65%表示在工作以外采取了行动。
在《招魂》一举成功后, 埃德·沃伦和罗琳·沃伦夫妇又推出了其续集《招魂2》。 影片讲述了1977年发生在伦敦的一个真实故事——恩菲德招灵事件。

该报道还指出经济更加发达的地区会有更多的网红,北京、上海、广东、江苏和浙江都位列前茅。
Company: Project Frog
考克斯说:“没人真正知道末日是什么样子的,上帝又会如何让末日降临。”
媒体非常令人讨厌,我们知道这一点,殿下,但您(以及您所代表的王室)可以用更有尊严的方式来表达您的关切。
统计数据显示,在2009年之前,全球研发支出以每年约7%的速度增长,但在2014年放缓了4%。
reform

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


住建部专家:今年中国房地产销售量或创历史新高


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


据《每日经济新闻》网报道,经过一项最新调查显示,经济和金融类院校毕业生最有'钱'途。国内5大财经类高校毕业生的平均月薪在1万元以上。
sur下面+rog要求…要求做下去…代理+ate表名词,“人或地位”→代理人,代替品
据预测,在大宗商品价格上涨和需求温和上升的推动下,2017年以美元计的新兴市场国家出口额将出现自2014年以来的首次增长。
The 8 per cent year-on-year drop in profits last month compares with 4.2 per cent in November and is the biggest since the current data series began in late 2011, figures released on Tuesday showed.
‘Unfortunately, while the newest episode may be a fantastic addition to the Star Wars franchise, ‘starwars’ is a dangerous password to use,’ said Morgan Slain, CEO of SplashData, Inc.
For the New Yorkers who have turned their apartments into bed-and-breakfasts, the battle over illegal inns could reach a fever pitch. On top of it all, Mayor Bill de Blasio’s 10-year affordable housing plan will take shape just as legislation in Albany threatens to strain the pocketbooks of renters. These are among the game-changers looming as we ring in the New Year.
Dachis says: Kraft took a stance in support of genetically engineered foods midway through the year and the decision turned their brand into an overall loser for 2012.
狗狗雨伞正流行。可爱又有趣的,也非常实用。
5. Constantly take action.
凯投宏观(Capital Economics)首席亚洲经济学家马克?威廉姆斯(Mark Williams)补充道:“我们预计,2017年新兴市场出口的表现将继续改善,出口值会同比温和增长。”

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the 提到MeToo行动,麦高恩说:“他们都是混蛋,不是冠军,一群失败者,我不喜欢他们。” to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

之所以会出现这一较低读数,是因为产量因素出现了下跌——尽管前瞻性新订单因素连续第6个月上升。
Company: Binary Group
Exports had risen in renminbi terms last month as well, up 5.9 per cent. But when valued in dollars they grew only 0.1 per cent year on year to $196.8bn. Still, that was well above expectations of a 5 per cent fall after contraction had softened somewhat in October to 7.3 per cent.
7. Trust will remain the single most critical business issue.

源于:Turkey土耳其,火鸡原产于土耳其地区。

  • Only the first three authors are listed, followed by "et al."
  • 9月份家居市场景气指数再攀升 三季度市场整体上涨
  • LED行业整体向好 龙头企业积极扩张


The number of candidates for the 2016 national civil service exam has surpassed last year's numbers, with more than 132,000 applicants on Tuesday-the most in a single day-deemed qualified for the exam.
布莱恩·肯德罗拉是纽约Stack's Bowers Galleries 拍卖行的行长,他透露这次拍卖吸引了来自6个国家的6名竞拍者。在星期四举行的拍卖会上,中标者是一名匿名的亚洲收藏家。

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