Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

Most female participants were between 19 and 23.
China has ample foreign exchange reserves to satisfy the demands of imports and short-term debt repayments.
"Apple, Google and Coca-Cola are the most valuable brands as their finances are strong, their brand is a powerful driver of choice and they are very strong compared to competitors," said Jez Frampton, Interbrand's global chief executive officer.
什么?他的公司利用贝南克印刷的低息钞票还没赚够?于是他将“增长速度降低”归咎于“财政紧缩”?就在贝南克错以为国会失灵、他才是美国的救星,所以继续以数万亿的规模吹胀美联储资产负债表泡沫的时候?
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5. Women keep rising.
Kay说我很一直很吃惊因为很多人都会告诉他们的同事找工作的事。这是你做的最糟糕的事情之一。理论上说你不能告诉任何同事,但是有时你不得不告诉他们因为想得到他们的引荐。如果那样的话Kay说,你得挑一些值得信任的人,他们不会背后秘密异议也不会口误说出去。
vi. 流通,循环,传播
9. Meghalaya, India-"Meghalaya won't stay this quiet for long; go before thrill seekers storm the Khasi Hills," advises Lonely Planet. Pictured is Nohkalikai Falls, India's tallest plunge waterfall at 340 meters.
下面是2014年的几部重现活力、需要刮目相看的老剧——以及几部死气沉沉的老剧。
回顾历史,单场进球数最多的比赛出现在1994年美国世界杯(俄罗斯6-1喀麦隆)。24支球队在52场比赛中场均进球2.97个。
据预测,在大宗商品价格上涨和需求温和上升的推动下,2017年以美元计的新兴市场国家出口额将出现自2014年以来的首次增长。
当城市规划部门明年初(2015年——译注)提出初步的建议方案时,布鲁克林的东纽约(East New York)地区将被列为试点。随后,重新区划进程就将在该处全市最穷社区之一内展开。而紧随其后的,将是针对皇后区的西法拉盛(Flushing)的提案。
美国演员、作家、时装设计师、舞蹈演员、制片人、歌手——拥有这么多头衔的珍妮弗·洛佩兹是2015年全球十大美女的亚军。作为一个结过三次婚的女星,洛佩兹的感情问题一直都是世界各国媒体关注的焦点。除涉足娱乐圈外,她还在商业领域颇有建树,其中包括经营服装、配饰、香水等。此外,她拥有一家制片公司,主持电视节目,还成立了一家慈善机构。
如果你在工作时间去寻找其他的工作岗位,很明显,你想要辞掉你的工作。去找一份新工作吧,如果找到,就换吧。
It is the first time that EMBA-Global, the joint programme delivered by London Business School and Columbia Business School, has dropped out of the top five.
In fact, one ancient saying was, "ifyou have Kucha, only one percent of the states in the Western Frontiers remain unsubmissive."
格里芬高中时代的样子与现今相差无几,原因是他离开高中才四年。我们能想象得出,暴力美学的格里芬在NBA里再锻炼上一两年年,他会变得更“怪兽”。
n. 通道,频道,(消息)渠道,海峡,方法
Make sure you've got a good plan for seeing that your children are cared for when you're scheduled to be in class, and when you need to study. It really is possible to raise children while you're going to school. People do it every day.
据一家行业报道,中国的网红预计能在2016年创造出高达580亿元(87亿美元)的市场,远超去年的440亿元的票房。
清华大学公共管理学院主任杨燕绥表示,这4万亿元养老金结余很多都在个人账户里面,现收现付的养老保险制度遇到了抚养比的挑战。
中国为世界人口最大国,总体排名为二十,被视为第三大强国,“创业最佳国”里排名第二。
The top 10 Weibo celebrities now have a combined 40 million followers. One of the most famous online figures, Papi Jiang, already signed a contract for video ads worth a staggering $3.4 million.
stick


ultimate
Harvard topped the league table, followed by Massachusetts Institute of Technology and Stanford University.
Vo said with each plane flying 12 to 16 segments a day, one late flight can easily cascade into several delays in a single day. To offset that, the airline’s systems operation and control center makes adjustments when needed. That can involve inserting spare planes and extra crews into the schedule to make sure flights stay on time.


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

cred相信+it表名词,通常是抽象名词→相信
Be Professional
TextPride是一门不错的生意,就是规模太小。与此同时,短信应用市场正在爆炸式增长。Facebook公司斥资190亿美元并购了WhatsApp,这款产品的每月活跃用户现已达到7亿人。拥有2.5亿注册用户的应用Tango目前市值15亿美元。Kik拥有2亿注册用户。Snapchat价值100亿美元,拥有一亿用户。Kik赞助的一项新研究表明,美国用户现在花在短信应用上的平均时间要多于社交网络应用。不过唯一的问题是,这些短信应用需要找到赚钱的手段,目前广告主还没找到靠谱的方式插入朋友间的聊天之中。
A report on entrepreneurship among Chinese college students published by Renmin University of China revealed an inverse proportion between the level of students' academic degrees and their intentions to start their own businesses.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

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Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

'He does smoke cigarettes, he smokes many, many cigarettes.
但是今年,研究者提出一种新的方法,这种方法可以通过真的细胞制作出有弹性真实的耳朵。这些细胞来自老鼠和奶牛,可以形成胶原凝胶,按任何模具成型。当放入使用3-D打印技术制作的耳朵模型后,一个小时内那些凝胶形成了一只假耳。在移植到对象之前,人造耳朵只需要在营养成分中生长培养几天。

n. 泄漏
12. Scientists modify photosynthesis to boost crop yield
“我们对中国在应对腐败问题上所做出的努力和取得的成功经验非常感兴趣。南非也面临腐败问题,耗费了我们很大精力。”南非政府最近提出了应对腐败的新举措。此举令人关注,因为这正出现在南非公共职能和行政事务部部长(琳迪韦·西苏鲁)访华之后。中国国家预防腐败局局长(马馼)参加了会见。这也体现出南非与中国领导人互访的益处。”Dr Bheki Langa, South African ambassador
今年的获奖榜单如下:
这个啤酒机能从下往上倒着灌满一杯好酒。
South Korean activists vowed Tuesday to sneak copies of Hollywood satire "The Interview" across the border by propaganda balloon later this month, in defiance of North Korea's repeated threats.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


亿光遭德法院封口 日亚化力争专利权


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


尽管每轮市场反弹最终都呈V形,每次连续的涨势中,个股的参与越来越少。今年春夏两季的绝大部分时间里,时事分析评论员们都专注于赢家与输家、大盘股和小盘股之间的明显差异。欧洲的通缩担忧以及日本的技术性衰退,使得分析师们愈加困惑,尽管美国经济正在好转,美国国库券收益率和通胀指标却双双下行。
Collins grew up in rural, apartheid-era South Africa in the 1970s. Her childhood inspired her to focus on empowering women living below the poverty line through grassroots efforts. The Wonderbag, which was inspired by watching her grandmother cook with cushions, uses heat retention technology to cook food for 8-12 hours without the need for additional fuel. Collins witnessed the benefits African women received from using Wonderbags, reducing the amount of time they spent collecting firewood. For every bag sold, another is donated to a household in Africa, and in the past four years, the Wonderbags have found themselves in 600,000 African homes. Collins has launched the Wonderbag in the U.S. on Amazon, and hopes to sell the products via other retailers by 2014.
The dollar value of exports from emerging market countries will rise next year for the first time since 2014, helped by higher commodity prices and modestly stronger demand, it is predicted.
GDP reached 74.4 trillion yuan, representing 6.7-percent growth.
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2010 10-year Treasury yield (year-end): 5.0%
狄更斯在《双城记》中描写法国大革命时,距离事件发生已有近一个世纪。而我则是在今年12月就回顾盘点这一年。因此,我在此描述的某些趋势,可能将在可预见的未来继续存在,而另一些趋势则可能已经开始减弱。作为当今时代“最哗众取宠的权威人士”之一,我只要求各位在阅读这篇评论文章时记住一点:过去的业绩并不能保证将来的表现。
民主党能在中期选举中重新夺回美国众议院多数党地位吗?
However, we are sceptical that the strength of imports can be sustained given that the delayed impact of policy tightening and a cooling property market are set to weigh on Chinese demand for commodities in coming quarters.
比蒂和唐纳薇上台宣布最佳影片奖时,卡利南和瑞兹意识到他们手里还有两只最佳影片信封,也就是说,拿上台的信封是已经宣布过的奖项。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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自从18个月前在亚洲设立业务以来,克拉布一直没有涉足香港房地产市场,因为他表示,价格太高了,可担负性太差。
determine
The Republican candidate appeared unsure at times and occasionally stumbled over his lines as if struggling to remember his briefing notes. He began sweating as Obama, aggressive from the start, got the better of him during exchanges on Iran, Iraq and Russia as well as on US military spending.
2. Mila Kunis

In Sex and the City, Miranda and Carrie frequent a place called Magnolia Bakery at 401 Bleeker Street. After the episodes aired, hordes of people had to investigate those cupcakes. Nothing can incur cupcake mania quite like Carrie Bradshaw can. Magnolia Bakery received a huge boost in sales and customers. In fact, they were so popular that they had to hire a "bouncer" of sorts. Not quite your typical club bouncer, this bouncer was friendly and very interested in the finer points of cupcakes.

  • Only the first three authors are listed, followed by "et al."
  • 李克强:保证就业就是要多策并举 让重点人群继续保持就业率
  • LED固装屏市场增速向好 2021年市场规模将达157亿美元


An escalating war on drugs in the Philippines has led to almost 1,800 deaths under new president Rodrigo Duterte, the country’s police chief has said.
n. 所有权

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